Calories in a slice of pizza depend on crust and toppings
A plain cheese slice runs about 285 calories, but thin crust drops near 150 and deep dish climbs past 500. Here is the calorie and protein count for every common pizza style, plus easy ways to enjoy a slice and still hit your numbers.

One regular slice of cheese pizza runs about 285 calories, and that plain slice is the floor, not the ceiling. The calories in a slice of pizza swing from around 150 for a thin crust wedge to nearly 500 for deep dish, so the honest answer depends on what you order.
So how many calories in a slice of pizza should you plan for on a normal night? A safe working number is 250 to 350 for a typical hand tossed slice, but crust thickness, cheese, and toppings each nudge it up. Below is the count for every common style, the whole pie math, and a few ways to keep pizza night from blowing your day.
How many calories in a slice of pizza by type
Style matters more than most people guess. A national calorie database puts the range at 150 to 480 calories per slice, from a thin crust cheese wedge at the low end to stuffed crust at the top. Those published slice ranges line up with what you would weigh at home. Here is how the popular styles stack up per slice.
| Pizza style | Calories | Protein |
|---|---|---|
| Neapolitan | 170 | 7 g |
| Standard cheese | 250 | 11 g |
| New York cheese | 350 | 16 g |
| Detroit square | 320 | 16 g |
| Chicago deep dish | 535 | 23 g |
| Personal pan | 135 | 5 g |
Cheese is the baseline, and every meat topping adds to it. Pepperoni tacks on roughly 50 calories a slice, and a stacked meat lovers slice can reach 400. Protein climbs right along with the calories, from about 7 grams in a small Neapolitan slice to 23 grams in a dense Chicago square.

A Chicago deep dish slice can hit 535 calories, nearly four times the 135 in a personal pan slice from a small pie.
Cheese pizza calories versus thin crust pizza calories
Cheese pizza calories depend almost entirely on the dough. A standard hand tossed cheese slice sits near 285 calories, while thin crust pizza calories drop to 150 to 200 because there is less bread under the sauce. The cheese and tomato barely change, so the crust is where you actually save.
There is one catch with thin crust. The slices are often smaller and easier to eat, so two thin slices can match one thick slice in calories. Track the count, not the feeling, and thin crust stays the lighter pick.

Pepperoni pizza calories and heavier toppings
Pepperoni pizza calories usually land between 290 and 330 per slice, roughly 40 to 50 more than plain cheese. If you are wondering how many calories in a slice of pizza with pepperoni you just grabbed, 310 is a fair estimate for a standard slice. The extra comes from the cured meat, which brings fat and salt along with the flavor.
Pepperoni, sausage, and bacon are the sodium heavy hitters. Each slice can carry 500 to 900 milligrams before you ever reach for the shaker.
Push past pepperoni and the numbers keep rising. Supreme and meat lovers slices run 350 to 400 calories, since sausage, bacon, and extra cheese each pile on. A veggie slice, by contrast, stays near 210 to 260 and gives you fiber instead of more fat.
How many slices in a large pizza and the whole pie math
Portion math is where pizza trips people up. A medium 12 inch pie is usually cut into 8 slices, so how many slices of pizza in a medium is almost always eight, and a large 14 inch is cut into 8 to 10. That means how many slices in a large pizza comes down to how your shop runs the cutter. Multiply the per slice number and the total gets real fast.

Nutritional value of a slice of pizza beyond calories
The nutritional value of a slice of pizza is not all bad news. A cheese slice carries about 11 to 12 grams of protein, 30 to 36 grams of carbs, and 10 to 11 grams of fat, so it eats like a real meal, not empty calories. Sodium is the number that deserves your attention.
| Pizza serving | Calories | Sodium |
|---|---|---|
| Cheese slice | 285 | 550 mg |
| Frozen 1/4 pie | 380 | 810 mg |
| Pizza Hut slice | 460 | 900 mg |
Restaurant and frozen slices run saltier than homemade. Pizza Hut nutrition data shows a Pepperoni Lovers slice near 460 calories and 900 milligrams of sodium, and a frozen pepperoni pizza is not far behind at 380 calories a quarter pie. One slice can cover a third of your daily salt.
One Pizza Hut Pepperoni Lovers slice packs about 900 milligrams of sodium, close to 38 percent of the daily limit in a single piece.

How to enjoy pizza and still hit your calorie goals
You do not have to quit pizza to lose weight. The move is to plan the slice into your day instead of pretending it did not happen. Log it first, count on 250 to 350 for a plain slice, and build the rest of your day around it. Our guide to counting macros makes those tradeoffs easy to see.
The fastest way to stay honest is to snap a photo of your plate before the first bite. A quick photo log turns a guessed slice into a tracked number, the same way it works for restaurant takeout or when you size portions by hand.
Common questions about pizza calories
How many calories in a slice of pizza with pepperoni?
A standard pepperoni slice runs about 290 to 330 calories, roughly 40 to 50 more than a plain cheese slice. The exact figure depends on how much pepperoni and cheese your shop piles on. For a quick estimate, plan on 310 calories a slice.
How many slices of pizza in a medium?
Most pizzerias cut a medium 12 inch pie into 8 slices. At about 250 calories each for cheese, that puts a whole medium near 2,000 calories, so two or three slices is a normal meal sized portion for most people.
How many calories in a piece of pizza from Pizza Hut?
Pizza Hut nutrition figures put a large Pepperoni Lovers slice near 460 calories with 900 milligrams of sodium. A plain cheese slice is lighter, closer to 300. Chains post full numbers online, so it pays to check before you order.
Is thin crust pizza lower in calories than deep dish?
Yes, and the gap is wide. Thin crust cheese runs 150 to 200 calories a slice, while Chicago deep dish can reach 535. Choosing thin crust over deep dish can save you more than 300 calories on a single slice.
Pizza fits a healthy diet once you know the number going in, and a plain slice near 285 calories leaves plenty of room to plan the rest of your day. Start tracking your meals today, download CalMeal for free, and take the guesswork out of calorie counting with AI powered food recognition. Get the app here: iOS or Android.